Penicillin-Resistant <i>Streptococcus pneumoniae</i> in Iran
نویسندگان
چکیده
منابع مشابه
Penicillin-resistant Streptococcus Pneumoniae
Streptococcus pneumoniae is a major cause of pneumonia, meningitis, septicemia, acute otitis media, and other serious infections, severely affecting infants, young children, and the elderly. In the past, S. pneumoniae was uniformly susceptible to penicillin, which remained the drug of choice for serious infections. However, since the mid-1960s, resistance to penicillin, which was first reported...
متن کاملDiversity of Mosaic pbp2x Families in Penicillin-Resistant Streptococcus pneumoniae from Iran and Romania
Penicillin-resistant Streptococcus pneumoniae strains are found at high rates in Romania and Iran. The mosaic structure of PBP2x was investigated in 9 strains from Iran and in 15 strains from Romania to understand their evolutionary history. Mutations potentially important for β-lactam resistance were identified by comparison of the PBP2x sequences with the sequence of the related PBP2x of refe...
متن کاملPenicillin resistant pneumococcus.
Resistance to other antimicrobial agents and chloramphenicol has also been reported. 4,5 Multiple resistant strains have been responsible for infection with a high mortality rate. 5 To our knowledge, isolation of penicillin resistant pneumococci has not been documented in this region. We report the isolation of a penicillin resistant strain from the throat of an eleven-month old baby boy and th...
متن کاملDaptomycin is highly efficacious against penicillin-resistant and penicillin- and quinolone-resistant pneumococci in experimental meningitis.
The penetration of daptomycin, a new lipopeptide antibiotic, into inflamed meninges ranged between 4.37 and 7.53% (mean, 5.97%). Daptomycin was very efficacious in the treatment of experimental pneumococcal meningitis, producing a decrease of -1.20 +/- 0.32 Deltalog(10) CFU/ml. h in the bacterial titer of Streptococcus pneumoniae against a penicillin-resistant strain and of -0.97 +/- 0.32 Delta...
متن کاملEfficacies of BMS 284756 against penicillin-sensitive, penicillin-resistant, and quinolone-resistant pneumococci in experimental meningitis.
BMS 284756 penetrated well into inflamed meninges (44% +/- 11%) and produced good bactericidal activity (-0.82 +/- 0.22 Delta log(10) CFU/ml. h) in the treatment of experimental meningitis in rabbits due to a penicillin-sensitive strain. BMS 284756 monotherapy had a greater potency than the standard regimen of ceftriaxone and vancomycin (-0.49 +/- 0.08 Delta log(10) CFU/ml. h) against a penicil...
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ژورنال
عنوان ژورنال: Medical Principles and Practice
سال: 2006
ISSN: 1011-7571,1423-0151
DOI: 10.1159/000096137